Daan Kromhout is (co-)author of more than 480 peer-reviewed publications and his work has been cited more than 28,000 times according to the Web of Science on 1 March 2014.

10 frequently cited publications:

Fish & fatty acids

  • Kromhout D, Bosschieter EB, De Lezenne Coulander C. The inverse relation between fish consumption and 20-year mortality from coronary heart disease. N Engl J Med 1985;312:1205 1209. Impact factor: 51.7, Citations: 1655
  • Kromhout D, Giltay EJ, Geleijnse JM for the Alpha Omega Trial Group. N-3 fatty acids and cardiovascular events after myocardial infarction. N Engl J Med 2010;363;21;2015-2026. Impact factor: 51.7, Citations: 194
  • Oomen CM, Ocke MC, Feskens EJ, Erp van-Baart MA, Kok FJ, Kromhout D. Association between trans fatty acid intake and 10-year risk of coronary heart disease in the Zutphen Elderly Study: a prospective population-based study. Lancet 2001;357:746-751. Impact factor: 39.1, citations: 230


  • Hertog MGL, Feskens EJM, Hollman PCH, Katan MB, Kromhout D. Dietary antioxidant flavonoids and risk of coronary heart disease. The Zutphen Elderly Study. Lancet 1993;342:1007-1012. Impact factor: 39.1, Citations: 2579
  • Hertog MGL, Kromhout D, Aravanis C, Blackburn H, Buzina R, Fidanza F, Giampaoli S, Jansen A, Menotti A, Nedeljkovic S, Pekkarinen M, Simic BS, Toshima H, Feskens EJM, Hollman PCH, Katan MB. Flavonoid intake and long-term risk of coronary heart disease and cancer in the Seven Countries Study. Arch Intern Med 1995;155:381-386. Impact factor: 11.5, Citations: 1149
  • Keli SO, Hertog GL, Feskens EJM, Kromhout D. Dietary flavonoids, antioxidant vitamins and incidence of stroke. The Zutphen Study. Arch Intern Med 1996;156:637-642. Impact factor: 11.5, citations: 565

Mediterranean style diet

  • Knoops KTB, Groot LCPGM de, Kromhout D, Perrin AE, Moreiras-Varela O, Menotti A, Staveren WA van. Mediterranean diet, lifestyle factors and 10-year mortality in elderly European men and women. JAMA 2004;292:1433-1439. Impact factor: 30.0, Citations: 554

Cholesterol, blood pressure & heart disease

  • Arntzenius AC, Kromhout D, Barth JD, Reiber JHC, Bruschke AVG, Buis B, Van Gent CM, Kempen Voogd N, Strikwerda S, Van der Velde EA. Diet, lipoproteins and the progression of coronary atherosclerosis. The Leiden Intervention Trial. N Engl J Med 1985;312:805 811. Impact factor: 51.7, Citations: 412
  • Verschuren WMM, Jacobs DR, Bloemberg BPM, Kromhout D, Menotti A, Aravanis C, Blackburn HW, Buzina R, Dontas AS, Fidanza F, Karvonen MJ, Nedeljkovic S, Nissinen A, Toshima H. Serum total cholesterol and long-term coronary heart disease mortality in different cultures. Twenty-five-year follow-up of the Seven Countries Study. JAMA 1995;274:131-136. Impact factor: 30.0, Citations: 279
  • Hoogen PC van den, Feskens EJ, Nagelkerke NJ, Menotti A, Nissinen A, Kromhout D, for the Seven Countries Study Research Group. The relation between blood pressure and mortality due to coronary heart disease among men in different parts of the world. N Engl J Med; 2000; 342; 1-8. Impact factor: 51.7, Citations: 260

For the full list of peer-reviewed publications, go to PubMed and search with Kromhout D[author].

Research in Practice

The capricious character of science is illustrated in this story for New England Journal of Medicine:

Daan Kromhout’s Fish Story (PDF)

Books and reviews

Daan is the first author of two books about the Seven Countries Study:

Prevention of coronary heart disease. Diet, lifestyle and risk factors in the Seven Countries Study.Kromhout D, Menotti A, Blackburn (Eds). Prevention of coronary heart disease. Diet, lifestyle and risk factors in the Seven Countries Study. Kluwer Academic Publishers, Norwell,MA,USA and Dordrecht, The Netherlands. ISBN 1-4020-7124-8. 2002:1-267.

The Seven Countries Study. A scientific adventure in cardiovascular epidemiology. Brouwer OffseKromhout D, Menotti A, Blackburn H (Eds). The Seven Countries Study. A scientific adventure in cardiovascular epidemiology. Brouwer Offset b.v., Utrecht 1994:1-219.

Recent review articles

Daan published the following recent reviews on fatty acids and coronary heart disease:

  • Kromhout D, Goede J de. Update on cardiometabolic health effects of omega-3 fatty acids. Curr Opin Lipidol 2014, 25:85-90
  • Kromhout D, Yasuda S, Geleijnse JM, Shimokawa H. Fish oil and omega-3 fatty acids in cardiovascular disease: do they really work? Eur Heart J 2012;33:436-443
  • Kromhout D, Geleijnse JM, Menotti A, Jacobs DR Jr. The confusion about dietary fatty acid recommendations for CHD prevention. Br J Nutr 2011;106:627-632